- The Student Government Association (SGA): The SGA serves as an advisory body to all chartered student organizations and clubs. SGA provides a forum for the exchange of ideas among members of the student body. Meetings are held every Wednesday at noon.
- 4 Seasons Club: Love the great outdoors? Skiing, snowboarding, horseback riding, hiking, camping or white-water rafting? We are the club for you!
- Black Student Union: A student club to create a safe space and community for African-American students on campus, to sponsor more ethnically-diverse events and advocate for African-American students.
- Blue and White Society: We are the student members of the Penn State Alumni Association. We provide opportunities to network with alumni, attend the Homecoming Parade at University Park, and more.
- Business and Entrepreneurial Club: A club for entrepreneurs, innovators and business professionals. We provide a platform for members to network, develop skills and entrepreneurial growth while making a positive impact on their careers, communities and the world at large!
- Lambda Sigma: We are the National Honor Society of surveying majors.
- Lion Ambassadors: We are the official student representatives and tour guides of Penn State Wilkes-Barre. Join us and learn to walk backwards!
- Nittany Gives: A student club focused on community service, promoting campus pride and engaging in a year-long philanthropy project each year.
- Game and Film Society: Are you a movie enjoyer, gamer or even just a casual pop culture fan? We are the place for you to express your pop culture feelings!
- Music Society: Got Talent? Open mic events, deejaying in the Student Commons, car shows and more!
- Students For Justice: Do you like watching Criminal Minds or CSI? Anyone with interest in the justice system is encouraged to join. We work on bringing to light criminal justice issues while also seeking to advance the concept of justice through community activities and campus projects.
- Surveying Society: Geocache, anyone? Lime green vests? We provide opportunities for our members to hear guest speakers, participate in field trips and attend state and national professional conferences.
- Penn State Wilkes-Barre Benefitting THON Committee: FTK... For the Kids! The largest student-run philanthropy in the world, THON is a year-long effort to raise funds and awareness for the fight against pediatric cancer, culminating in a 48-hour dance marathon to raise money for the Four Diamonds Fund at the Hershey Medical Center. Help us help them!
- Veterans Support Club (VSC): We are a group of veterans, ROTC, active-duty, reservist, and supporters who work to support and raise awareness of veterans on campus. Additionally, we look to assist veterans within the local community.